Product Name:CRF (human,rat)
CAS No.:86784-80-7
Synonyms:Corticotropin Releasing Factor, human, rat;促肾上腺皮质激素释放因子
Catalog No.:131P03
Brand:HongTide(上海鸿肽生物)
Description:CRF (human,rat)是一种肾上腺皮质素释放因子多肽,序列中含有41个氨基酸,人源与鼠源序列相同,能够刺激垂体前叶的促肾上腺皮质激素的合成和分泌。CRF 通过激活 AC-cAMP-PKA 通路增加 II 型 dlBNST 神经元的兴奋性,从而引起疼痛诱导的厌恶反应。
CRF (human, rat) is a kind of adrenocorticin-releasing factor polypeptide with 41 amino acids in its sequence. The sequence of human and mouse is the same, which can stimulate the synthesis and secretion of adrenocorticotropin in the anterior pituitary. CRF increases the excitability of type II dlBNST neurons by activating the AC-cAMP-PKA pathway, thus causing pain-induced aversion.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | SEEPPISLDLTFHLLREVLEMARAEQLAQQAHSNRKLMEII-NH2 |
Sequence(3-letter code) | H-Ser-Glu-Glu-Pro-Pro-Ile-Ser-Leu-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Glu-Val-Leu-Glu-Met-Ala-Arg-Ala-Glu- Gln-Leu-Ala-Gln-Gln-Ala-His-Ser-Asn-Arg-Lys-Leu-Met-Glu-Ile-Ile-NH2 |
Peptide Structure | ![CRF (human, rat) 86784-80-7.png CRF (human, rat) 86784-80-7.png](/SupplyImg/2023-03-14/6381442446949694698375671.jpg)
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Molecular Formula | C208H344N60O63S2 |
Molecular Weight | 4575.51 |
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关键字: 86784-80-7;促肾上腺皮质激素释放因子;CRF (human, rat);多肽;多肽合成;
上海鸿肽生物科技有限公司(简称:鸿肽生物)是一家以多肽以及多肽上下游产品研发、生产、销售以及技术转让为主要业 务科技公司。公司现有产品涵盖:定制多肽、目录多肽、氨基酸衍生物、小分子化合物;公司自成立以来,秉持“用质量作船, 以服务为帆,为科研服务”的企业理念,为国内外众多科研工作者提供了优质的服务及产品。