Product Name:α-Conotoxin SIA
CAS No.:135190-31-7
Synonyms:α-芋螺毒素 SIA
Catalog No.:218P036
Brand:HongTide(上海鸿肽)
Description:α-Conotoxin SIA是SIA型α-芋螺毒素系列中的一种序列,由13个氨基酸组成,结构中含有两对二硫键。α-Conotoxin SIA是一种对肌肉nAChR具有高亲和力的选择性烟碱乙酰胆碱受体(nAChR拮抗剂多肽,α-Conotoxin SIA优先靶向小鼠肌肉nAChR的α/δ界面。相比之下,对于鱼雷nAChR,α-Conotoxin SIA对α/γ的亲和力远高于α/δ界面的亲和力。
α- Conotoxin SIA is SIA type sequence of α- Conotoxin, consisting of 13 amino acids, containing two pairs of disulfide bonds. α- Conotoxin SIA is a selective nicotinic acetylcholine receptor (nAChR antagonist polypeptide) with high affinity for muscle nAChR, α- Conotoxin SIA preferentially targets the muscle nAChR of mice α/δ Interface. In contrast, for torpedo nAChR, α- Conotoxin SIA pair α/γ The affinity is much higher than α/δ Interface affinity.
Purity (HPLC) ≥95.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | YCCHPACGKNFDC-NH2(Disulfide bridge:Cys2-Cys7;Cys3-Cys13) |
Sequence(3-letter code) | H-Tyr-Cys-Cys-His-Pro-Ala-Cys-Gly-Lys-Asn-Phe-Asp-Cys-NH2(Disulfide bridge: Cys2-Cys7,Cys3-Cys13) |
Peptide Structure | ![α-Conotoxin SIA 135190-31-7.jpg α-Conotoxin SIA 135190-31-7.jpg](/SupplyImg/2023-03-16/6381457232691325277252180.jpg)
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Molecular Formula | C60H82N18O17S4 |
Molecular Weight | 1455.66 |
订购联系方式:
上海鸿肽生物科技有限公司
手机: +86-18018095145 (同微信号)
QQ: 3259098395
邮箱:sales1@hongtide.com
关键字: 135190-31-7;α-Conotoxin SIA;α-芋螺毒素 SIA;多肽;芋螺毒素;
上海鸿肽生物科技有限公司(简称:鸿肽生物)是一家以多肽以及多肽上下游产品研发、生产、销售以及技术转让为主要业 务科技公司。公司现有产品涵盖:定制多肽、目录多肽、氨基酸衍生物、小分子化合物;公司自成立以来,秉持“用质量作船, 以服务为帆,为科研服务”的企业理念,为国内外众多科研工作者提供了优质的服务及产品。