Product Name:Linaclotide
CAS No.:851199-59-2;851199-60-5
Synonyms:linaclotide (usan);利那洛肽
Catalog No.:218P053
Brand:HongTide(上海鸿肽)
Description:利那洛肽是一种鸟苷酸环化酶C激动剂,结构为含14个氨基酸的多肽。该药物多肽能通过与肠道上皮局部的GC-C受体结合发挥作用,活化后的GC-C受体诱导体内cGMP浓度增加,一方面可以刺激肠液的分泌并促进胃肠活动,导致患者排便次数增多;另一方面可以减少痛觉神经活性,进而减少患者肠道疼痛。
Linaclotide is a guanylate cyclase C agonist with a structure of a peptide containing 14 amino acids. The drug peptide can play a role by binding to local GC-C receptors in the intestinal epithelium, and the activated GC-C receptors can induce an increase in the concentration of cGMP in the body. On the one hand, it can stimulate the secretion of intestinal fluid and promote gastrointestinal activity, leading to an increase in the number of stools in patients; On the other hand, it can reduce pain sensory nerve activity, thereby reducing intestinal pain in patients.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | CCEYCCNPACTGCY(Disulfide bond:Cys1-Cys6, Cys2 -Cys10,Cys5-Cys13) |
Sequence(3-letter code) | H-Cys-Cys-Glu-Tyr-Cys-Cys-Asn-Pro-Ala-Cys-Thr-Gly-Cys-Tyr-OH (Disulfide bond:Cys1-Cys6, Cys2-Cys10,Cys5-Cys13) |
Peptide Structure | ![微信截图_20230321201115.png 微信截图_20230321201115.png](/SupplyImg/2023-03-21/6381502632752567305159492.jpg) |
Molecular Formula | C59H79N15O21S6 |
Molecular Weight | 1526.74 |
订购联系方式:
上海鸿肽生物科技有限公司
手机: +86-18018095145 (同微信号)
QQ: 3259098395
邮箱:sales1@hongtide.com
关键字: 851199-59-2;851199-60-5;利那洛肽;Linaclotide;多肽;
上海鸿肽生物科技有限公司(简称:鸿肽生物)是一家以多肽以及多肽上下游产品研发、生产、销售以及技术转让为主要业 务科技公司。公司现有产品涵盖:定制多肽、目录多肽、氨基酸衍生物、小分子化合物;公司自成立以来,秉持“用质量作船, 以服务为帆,为科研服务”的企业理念,为国内外众多科研工作者提供了优质的服务及产品。