Product Name:Pasireotide
CAS No.:396091-73-9;396091-76-2
Synonyms:SOM230;帕西瑞肽
Catalog No.:218P051
Brand:HongTide(上海鸿肽)
Description:帕西瑞肽是一种结构为环六肽的生长抑素类似物,序列中含有4个非天然氨基酸,作为药物主要成分的帕西瑞肽适用于未进行垂体手术或手术未治愈的库欣氏病成年患者的治疗。同奥曲肽相比,帕西瑞肽有更长的半衰期、能与更多受体结合,抑制胰腺分泌,抑制肠道蛋白水解酶的活性,通过这些机制来降低胰腺术后并发症。
Pasireotide is a somatostatin analogue with a cyclic hexapeptide structure and contains four unnatural amino acids in its sequence. As a main component of the drug, Pasireotide is suitable for the treatment of adult patients with Cushing's disease who have not undergone pituitary surgery or have not been cured by surgery. Compared with octreotide, Pasireotide has a longer half life, can bind to more receptors, inhibit pancreatic secretion, and inhibit the activity of intestinal proteolytic enzymes. These mechanisms can reduce postoperative complications of pancreatic surgery.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | cyclo[Y(Bzl)F-Hyp(Bom)-Phg-d-W-K] |
Sequence(3-letter code) | cyclo[Tyr(Bzl)-Phe-Hyp(Bom)-Phg-D-Trp-Lys] |
Peptide Structure | ![Pasireotide 396091-73-9;396091-76-2.png Pasireotide 396091-73-9;396091-76-2.png](/SupplyImg/2023-03-22/6381508140893874627036033.jpg)
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Molecular Formula | C58H66N10O9 |
Molecular Weight | 1047.21 |
订购联系方式:
上海鸿肽生物科技有限公司
手机: +86-18018095145 (同微信号)
QQ: 3259098395
邮箱:sales1@hongtide.com
关键字: 396091-73-9;396091-76-2;Pasireotide;帕西瑞肽;多肽;
上海鸿肽生物科技有限公司(简称:鸿肽生物)是一家以多肽以及多肽上下游产品研发、生产、销售以及技术转让为主要业 务科技公司。公司现有产品涵盖:定制多肽、目录多肽、氨基酸衍生物、小分子化合物;公司自成立以来,秉持“用质量作船, 以服务为帆,为科研服务”的企业理念,为国内外众多科研工作者提供了优质的服务及产品。