Product Name:Urocortin II,mouse
CAS No.:330648-32-3
Synonyms:Ucn II (mouse);尾加压素(小鼠)
Catalog No.:206P08
Brand:HongTide(上海鸿肽生物)
Description:Urocortin II,mouse是2型促肾上腺皮质激素释放因子(CRF2)受体的有效和选择性内源性肽激动剂多肽,是由38个氨基酸组成的直链多肽,固相合成工艺较难。Urocortin II,mouse的Ki值为0.66nM﹥CRFR2和CRFR1分别为100nM。Urocortin II,mouse以cAMP/PKA-和Ca2+/CaMKII依赖的方式激活CRF2受体,在中枢神经系统的离散区域表达,并激活参与内脏感觉信息处理和调节自主神经流出的中枢神经元。
Urocortin II, mouse is an effective and selective endogenous peptide agonist peptide for the type 2 adrenocorticotropin releasing factor (CRF2) receptor. It is a straight chain polypeptide composed of 38 amino acids, and the solid-state synthesis process is difficult. The Ki value of Urocortin II and mouse is 0.66 nM>CRFR2 and CRFR1 are 100 nM, respectively. Urocortin II, mouse activates the CRF2 receptor in a cAMP/PKA - and Ca2+/CaMKII dependent manner, expresses in discrete regions of the central nervous system, and activates central neurons involved in visceral sensory information processing and regulating autonomic nerve outflow.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | VILSLDVPIGLLRILLEQARYKAARNQAATNAQILAHV-NH2 |
Sequence(3-letter code) | H-Val-Ile-Leu-Ser-Leu-Asp-Val-Pro-Ile-Gly-Leu-Leu-Arg-Ile-Leu-Leu-Glu-Gln-Ala-Arg-Tyr-Lys-Ala-Ala-Arg-Asn-Gln-Ala-Ala-Thr-Asn-Ala-Gln-Ile-Leu-Ala-His-Val-NH2 |
Peptide Structure | |
Molecular Formula | C187H320N56O50 |
Molecular Weight | 4152.98 |
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关键字: 330648-32-3;Urocortin II,mouse;尾加压素(小鼠);多肽;多肽合成;
上海鸿肽生物科技有限公司(简称:鸿肽生物)是一家以多肽以及多肽上下游产品研发、生产、销售以及技术转让为主要业 务科技公司。公司现有产品涵盖:定制多肽、目录多肽、氨基酸衍生物、小分子化合物;公司自成立以来,秉持“用质量作船, 以服务为帆,为科研服务”的企业理念,为国内外众多科研工作者提供了优质的服务及产品。