别名
4,5,6,7-Tetrachloro-2,3-dihydro-2-methyl-2-[2-(trimethylammonio)ethyl]-2H-isoindolium diiodide
应用
Chlorisondamine diiodide has been used:as a nicotinic receptor antagonist to test its effect on trinitrobenzene sulfonic acid (TNBS)-induced colitisas an irreversible nicotinic acetylcholine(nAChR) blocker to pre-treat brain samples to test its effect on cytochrome P450 2B (CYP2B) inductionas a ganglionic blocker to test its effect on regulating corticosterone levels in rat with chronic stress
生化/生理作用
Chlorisondamine diiodide mediates ganglionic and central blockade. Irreversible, long-lasting nicotinic acetylcholine receptor antagonist.
Sigma-Aldrich西格玛奥德里奇(上海)贸易有限公司
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