Product Name：Fz7-21
CAS No.：2247635-23-8
Synonyms：拮抗剂多肽Fz7-21
Catalog No.：218P101
Brand：HongTide（上海鸿肽生物）
Description：Fz7-21是一种FZD7（FZD7）受体的肽拮抗剂，由14个氨基酸组成，肽链的两端均被封闭，选择性地与FZD7-CRD亚类结合。人和小鼠FZD7-CRD的EC50值分别为58和34nm。Fz7-21在外源性WNT3A（IC50=100 nM）刺激或转染表达WNT3A或WNT1的HEK293细胞中削弱Wnt/β-catenin信号传导。小鼠β2 1-3nM细胞的稳定化作用。
Fz7-21 is a peptide antagonist of the FZD7 (FZD7) receptor, composed of 14 amino acids, with both ends of the peptide chain blocked and selectively binding to the FZD7-CRD subclass. The EC50 values of human and mouse FZD7-CRD were 58 and 34 nm, respectively. Fz7-21 attenuates Wnt in HEK293 cells expressing WNT3A or WNT1 stimulated or transfected with exogenous WNT3A (IC50=100 nM)/ β- Catenin signal transduction. mice β The stabilization effect of 2 1-3nM cells.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | Ac-LPSDDLEFWCHVMY-NH2 |
Sequence(3-letter code) | Ac-Leu-Pro-Ser-Asp-Asp-Leu-Glu-Phe-Trp-Cys-His-Val-Met-Tyr-NH2 |
Peptide Structure | 
|
Molecular Formula | C83H114N18O23S2 |
Molecular Weight | 1796.04 |
订购联系方式：
上海鸿肽生物科技有限公司
手机： +86-18018095145 （同微信号）
QQ: 3259098395
邮箱：sales1@hongtide.com
关键字： 2247635-23-8;Fz7-21;拮抗剂多肽Fz7-21;多肽合成;多肽;
上海鸿肽生物科技有限公司（简称：鸿肽生物）是一家以多肽以及多肽上下游产品研发、生产、销售以及技术转让为主要业 务科技公司。公司现有产品涵盖：定制多肽、目录多肽、氨基酸衍生物、小分子化合物；公司自成立以来，秉持“用质量作船， 以服务为帆，为科研服务”的企业理念，为国内外众多科研工作者提供了优质的服务及产品。