Product Name:LL-37 FKR
CAS No.:913736-94-4
Synonyms:LL-37 (17-37);Cationic Antimicrobial Protein 18 (150-170) (human),hCAP-18 (150-170);人源性抗菌肽LL-37 FKR
Catalog No.:112P47
Brand:HongTide(上海鸿肽生物)
Description:LL-37 是人体内发现的唯一的一种Cathelicidin 类抗菌肽,LL-37是由前体hCAP-18 经丝氨酸蛋白酶3剪切后产生。大量研究发现,LL-37 可在卵巢癌、肺癌、恶性黑色素瘤、皮肤鳞状细胞癌、前列腺癌等肿瘤中发挥促癌作用;而在胃癌、结直肠癌、白血病等肿瘤中发挥抑癌作用,因此对LL-37的研究具有很大的潜力。LL-37 FKR是从LL-37序列中选取第17个氨基酸至第37个氨基酸片段,保留了大部分的生理学功能。
LL-37 is the only Catalicidin class antimicrobial peptide found in the human body, and is produced by the precursor hCAP-18 after being cleaved by serine protease 3. A large number of studies have found that LL-37 can play a cancer promoting role in ovarian cancer, lung cancer, malignant melanoma, skin squamous cell carcinoma, prostate cancer and other tumors; And it plays an inhibitory role in tumors such as gastric cancer, colorectal cancer, and leukemia, so the research on LL-37 has great potential. LL-37 FKR selects the 17th to 37th amino acid fragments from the LL-37 sequence, preserving most of its physiological functions.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | FKRIVQRIKDFLRNLVPRTES |
Sequence(3-letter code) | H-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser-OH |
Peptide Structure | ![LL-37 FKR 913736-94-4.png LL-37 FKR 913736-94-4.png](/SupplyImg/2023-04-04/6381621640202806949142095.jpg)
|
Molecular Formula | C118H199N37O30 |
Molecular Weight | 2616.11 |
订购联系方式:
上海鸿肽生物科技有限公司
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邮箱:sales1@hongtide.com
关键字: LL-37 FKR;913736-94-4;源性抗菌肽LL-37 FKR;抗菌肽;多肽;
上海鸿肽生物科技有限公司(简称:鸿肽生物)是一家以多肽以及多肽上下游产品研发、生产、销售以及技术转让为主要业 务科技公司。公司现有产品涵盖:定制多肽、目录多肽、氨基酸衍生物、小分子化合物;公司自成立以来,秉持“用质量作船, 以服务为帆,为科研服务”的企业理念,为国内外众多科研工作者提供了优质的服务及产品。