Product Name:MeOSuc-AAPV-pNA
CAS No.:70967-90-7
Synonyms:高敏感底物多肽
Catalog No.:140P198
Brand:HongTide(上海鸿肽生物)
Description:蛋白酶3(PR3,成髓细胞素)是一种多形核白细胞丝氨酸蛋白酶,可降解基质蛋白,包括纤连蛋白、层粘连蛋白、玻连蛋白和 IV 型胶原蛋白,以生成抗菌肽。 中性粒细胞弹性蛋白酶是一种丝氨酸蛋白酶,在炎症期间由中性粒细胞分泌以破坏病原体。评估这些酶有助于了解炎症性自身免疫过程。MeOSuc-AAPV-pNA是一种高度敏感的肽底物,可被人和小鼠中性粒细胞弹性蛋白酶和PR3水解,但不被组织蛋白酶G或胰凝乳蛋白酶水解。 酶活性可以通过在405nm处比色检测游离对硝基苯胺来量化。
Protease 3 (PR3, myeloblastin) is a polymorphonuclear leukocyte serine protease that can degrade matrix proteins, including fibronectin, laminin, Vitronectin and type IV collagen, to generate antibacterial peptides. Neutrophil Elastase is a serine protease that is secreted by neutrophils during inflammation to destroy pathogens. Evaluating these enzymes helps to understand inflammatory autoimmune processes. MeOSuc-AAPV pNA is a highly sensitive peptide substrate, which can be hydrolyzed by human and mouse neutrophil Elastase and PR3, but not by cathepsin G or chymotrypsin. Enzyme activity can be quantified by colorimetric detection of free p-nitroaniline at 405nm.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | MeOSuc-AAPV-pNA |
Sequence(3-letter code) | MeOSuc-Ala-Ala-Pro-Val-pNA |
Peptide Structure | ![MeOSuc-AAPV-pNA 70967-90-7.png MeOSuc-AAPV-pNA 70967-90-7.png](/SupplyImg/2023-04-13/6381697934291475034975758.jpg) |
Molecular Formula | C27H38N6O9 |
Molecular Weight | 590.61 |
订购联系方式:
上海鸿肽生物科技有限公司
手机: +86-18018095145 (同微信号)
QQ: 3259098395
邮箱:sales1@hongtide.com
关键字: 70967-90-7;MeOSuc-AAPV-pNA;高敏感底物多肽;多肽;多肽合成;
上海鸿肽生物科技有限公司(简称:鸿肽生物)是一家以多肽以及多肽上下游产品研发、生产、销售以及技术转让为主要业 务科技公司。公司现有产品涵盖:定制多肽、目录多肽、氨基酸衍生物、小分子化合物;公司自成立以来,秉持“用质量作船, 以服务为帆,为科研服务”的企业理念,为国内外众多科研工作者提供了优质的服务及产品。