Product Name:[Sar1,Ile4,8]-Angiotensin II
CAS No.:185461-45-4
Synonyms:[Sar1,Ile4,8]-血管紧张素II
Catalog No.:108P19
Brand:HongTide(上海鸿肽生物)
Description:[Sar1,Ile4,8]-Angiotensin II是血管紧张素II的改造片段多肽,保留了序列中的第1-8位氨基酸,并且第1位的氨基酸由Asp换成了Sar,第4位的Tyr和第8位的Phe均换成Ile。[Sar1,Ile4,8]-Angiotensin II可通过血管紧张素 II 1A 型受体激活细胞外信号调节激酶 1 和 2 (ERK1/2),同时能激活取决于 β-抑制蛋白2的表达。
[Sar1, Ile4,8] - Angiotensin II is a modified peptide fragment of angiotensin II, retaining the amino acids in positions 1-8 of the sequence. The amino acid in position 1 was replaced with Sar by Asp, while Tyr in position 4 and Phe in position 8 were replaced with Ile. [Sar1, Ile4,8] - Angiotensin II can activate extracellular signal-regulated kinases 1 and 2 (ERK1/2) through the angiotensin II type 1A receptor, and its activation depends on β- Suppress the expression of protein 2.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | Sar-RVIIHPI |
Sequence(3-letter code) | H-Sar-Arg-Val-Ile-Ile-His-Pro-Ile-OH |
Peptide Structure | ![[Sar1,Ile4,8]-Angiotensin II 185461-45-4.png [Sar1,Ile4,8]-Angiotensin II 185461-45-4.png](/SupplyImg/2023-04-18/6381742382531773229638518.jpg)
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Molecular Formula | C43H75N13O9 |
Molecular Weight | 918.15 |
订购联系方式:
上海鸿肽生物科技有限公司
手机: +86-18018095145 (同微信号)
QQ: 3259098395
邮箱:sales1@hongtide.com
关键字: 185461-45-4;[Sar1,Ile4,8]-Angiot;[Sar1,Ile4,8]-血管紧张素I;多肽;多肽合成;
上海鸿肽生物科技有限公司(简称:鸿肽生物)是一家以多肽以及多肽上下游产品研发、生产、销售以及技术转让为主要业 务科技公司。公司现有产品涵盖:定制多肽、目录多肽、氨基酸衍生物、小分子化合物;公司自成立以来,秉持“用质量作船, 以服务为帆,为科研服务”的企业理念,为国内外众多科研工作者提供了优质的服务及产品。