Host:Rabbit
Target Protein:NALP3/CIAS1
IR:Immunogen Range:15-120/1036
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:114548
Swiss Prot:Q96P20
Source:KLH conjugated synthetic peptide derived from human Cryopyrin:15-120/1036
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:May function as an inducer of apoptosis. Interacts selectively with ASC and this complex may function as an upstream activator of NF-kappa-B signaling. Inhibits TNF-alpha induced activation and nuclear translocation of RELA/NF-KB p65. Also inhibits transcriptional activity of RELA. Activates caspase-1 in response to a number of triggers including bacterial or viral infection which leads to processing and release of IL1B and IL18.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(2ug/Test)
IF(1:200-800)
Cross Reactive Species:Human
Mouse
Rat
Dog
本产品仅供科研使用。不能用于人和动物治疗等其它临床诊断使用！
关键字： NALP3/CIAS1;NALP3/CIAS1;NACHT;CIAS1;CIAS 1;
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