Host:Rabbit
Target Protein:Phospho-JNK1/2/3(T183+T183+T221)
IR:Immunogen Range:MM(p-T)PY
Clonality:Monoclonal
Isotype:IgG
Entrez Gene:5599
Swiss Prot:P45983
Source:KLH conjugated Synthesised phosphopeptide derived from human JNK1/JNK2/JNK3 around the phosphorylation site of T183/T183/T221:MM(p-T)PY
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Five alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jun 2013]
Size:50ul
Concentration:1mg/ml
Applications:WB(1:1000-2000)
IP(1:20-50)
IHC-P(1:50-200)
IHC-F(1:50-200)
Flow-Cyt(1:100)
ICC(1:50)
Cross Reactive Species:Human
Mouse
Rat
.
本产品仅供科研使用。不能用于人和动物治疗等其它临床诊断使用！
关键字： AI849689; MK10_HUMAN;SAPK1;PRKM8;JAK1A;
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