Host:Rabbit
Target Protein:ADRB2
IR:Immunogen Range:
Clonality:Monoclonal
Isotype:IgG
Entrez Gene:154
Swiss Prot:P07550
Source:KLH conjugated synthetic peptide derived from human ADRB2:
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Beta 2 Adrenergic Receptor is a member of the G protein coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L type calcium channel Ca(V)1.2. This receptor channel complex also contains a G protein, an adenylyl cyclase, cAMP dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein coupled receptor. This gene contains no introns in either its coding or untranslated sequences. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. Expression of the beta 2 Adrenergic Receptor has been reported in adipose, blood, brain, heart, lung, nose, pancreas, skeletal muscle, skin, and vessel.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
IHC-P(1:50-100)
Flow-Cyt(1:100)
ICC(1:100)
Cross Reactive Species:Human
Mouse
Rat
Zebrafish
本产品仅供科研使用。不能用于人和动物治疗等其它临床诊断使用！
关键字： ADRB2;ADRBR;ADRB2R;BAR;B2AR;
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