Host:Rabbit
Target Protein:MRE11
IR:Immunogen Range:
Clonality:Monoclonal
Isotype:IgG
Entrez Gene:4361
Swiss Prot:P49959
Source:Recombinant human MRE11:
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-1000)
IHC-P(1:50-200)
Cross Reactive Species:Human
Mouse
Rat
![搜狗截图23年04月27日1010_234.png 搜狗截图23年04月27日1010_234.png](/SupplyImg/2023-04-27/6381818702259759672659237.jpg)
本产品仅供科研使用。不能用于人和动物治疗等其它临床诊断使用!
关键字: HNGS1;Mre 1;Mre 11a;MRE 11b;MRE11a;
上海沪震实业有限公司是一家集研发、生产和销售于一体的生命科学实验室产品生物科技企业。主营产品:试剂盒,ELISA试剂盒,抗体,重组蛋白,血清,胎牛血清,细胞,原代细胞 细胞培养试剂,常用生化试剂。