Host:Rabbit
Target Protein:Phospho-SIRT1 (Ser47)
IR:Immunogen Range:R(p-S)PG
Clonality:Monoclonal
Isotype:IgG
Entrez Gene:23411
Swiss Prot:Q96EB6
Source:KLH conjugated Synthesised phosphopeptide derived from human SirT1 around the phosphorylation site of Ser47:R(p-S)PG
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]
Size:50ul
Concentration:1mg/ml
Applications:WB(1:1000)
IHC-P(1:50-200)
ICC(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
本产品仅供科研使用。不能用于人和动物治疗等其它临床诊断使用！
关键字： SIR2L1;EC:2.3.1.286;hSIRT1Phospho-SIRT1 ;SIR1_HUMAN;hSIRT1;
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