Host:Rabbit
Target Protein:SUN2
IR:Immunogen Range:
Clonality:Monoclonal
Isotype:IgG
Entrez Gene:25777
Swiss Prot:Q9UH99
Source:Recombinant protein within human SUN2 aa 500-700.:
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:SUN1 (MIM 607723) and SUN2 are inner nuclear membrane (INM) proteins that play a major role in nuclear-cytoplasmic connection by formation of a 'bridge' across the nuclear envelope, known as the LINC complex, via interaction with the conserved luminal KASH domain of nesprins (e.g., SYNE1; MIM 608441) located in the outer nuclear membrane (ONM). The LINC complex provides a direct connection between the nuclear lamina and the cytoskeleton, which contributes to nuclear positioning and cellular rigidity (summary by Haque et al., 2010 [PubMed 19933576]).[supplied by OMIM, Nov 2010]
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
IHC-P(1:50-200)
ICC(1:50-100)
Cross Reactive Species:.
本产品仅供科研使用。不能用于人和动物治疗等其它临床诊断使用！
关键字： FRIGG ;KIAA0668 ;UNC84B ;UNC 84B;RAB5IP ;
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