Host:Rabbit
Target Protein:DOPA Decarboxylase
IR:Immunogen Range:201-300/480
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:1644
Swiss Prot:P20711
Source:KLH conjugated synthetic peptide derived from human DDC:201-300/480
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:DOPA decarboxylase is an enzyme implicated in 2 metabolic pathways, synthesizing 2 important neurotransmitters: dopamine and serotonin which both play key roles in many clinical disorders, including Parkinson's disease. Following the hydroxylation of tyrosine to form L dihydroxyphenylalanine (LDOPA), catalyzed by tyrosine hydroxylase, DDC decarboxylates LDOPA to form dopamine. This neurotransmitter is found in different areas of the brain and is particularly abundant in basal ganglia. Dopamine is also produced by DDC in the sympathetic nervous system and is the precursor of the catecholaminergic hormones, noradrenaline and adrenaline in the adrenal medulla. In the nervous system, tryptophan hydroxylase produces 5 OH tryptophan, which is decarboxylated by DDC, giving rise to serotonin. DDC is a homodimeric, pyridoxal phosphate dependent enzyme.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
![搜狗截图23年04月27日1422_270.png 搜狗截图23年04月27日1422_270.png](/SupplyImg/2023-04-27/6381820219523942225034600.jpg)
本产品仅供科研使用。不能用于人和动物治疗等其它临床诊断使用!
关键字: AADC;DDC;DDC protein;DDC_HUMAN;DOPA Decarboxylase;
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