Host:Rabbit
Target Protein:IL6ST/CD130
IR:Immunogen Range:651-750/917
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:3572
Swiss Prot:P40189
Source:KLH conjugated synthetic peptide derived from human IL6R beta:651-750/917
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:CD130 is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggested a critical role of the gene encoding this protein in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(1µg/Test)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
本产品仅供科研使用。不能用于人和动物治疗等其它临床诊断使用！
关键字： IL6ST/CD130;CD130;IL6ST;GP130 RAPS; IL6R-beta;
上海沪震实业有限公司是一家集研发、生产和销售于一体的生命科学实验室产品生物科技企业。主营产品：试剂盒，ELISA试剂盒，抗体，重组蛋白，血清，胎牛血清，细胞，原代细胞 细胞培养试剂，常用生化试剂。