Product Name：Laminin (925-933)
CAS No.：110590-60-8
Synonyms：层粘连蛋白(925-933)
Catalog No.：168P02
Brand：HongTide（上海鸿肽生物）
Description：Laminin (925-933) acetate是由9个氨基酸组成的直链多肽，源自与层粘连蛋白受体结合的层粘连蛋白 B1 链的残基 925-933。层粘连蛋白是细胞外基质糖蛋白家族，是基底膜的主要非胶原成分。它们与多种生物过程有关，包括细胞粘附、分化、迁移、信号传导、神经突生长和转移。层粘连蛋白由 3 条不同的链组成：层粘连蛋白 α、β 和 γ（以前分别为 A、B1 和 B2）。层粘连蛋白 β 1 链具有 7 个结构不同的结构域，它与其他 β 链异构体共享这些结构域。层粘连蛋白，β1 在大多数产生基底膜的组织中表达，并且是构成层粘连蛋白 1 的 3 条链之一，层粘连蛋白 1 是从 Engelbreth-Holm-Swarm (EHS) 肿瘤中分离的个层粘连蛋白。 β1 链中涉及细胞附着、趋化性和与层粘连蛋白受体结合的序列被鉴定并显示具有抑制转移的能力。
Laminin (925-933) acetate is a straight chain peptide composed of 9 amino acids, derived from the residue 925-933 of the laminin B1 chain that binds to the laminin receptor. Laminin is a family of extracellular matrix glycoproteins that are the main non collagen component of the basement membrane. They are involved in a variety of biological processes, including cell adhesion, differentiation, migration, signal transduction, neurite growth and metastasis. Laminin is composed of three different chains: laminin α、β And γ (Previously A, B1, and B2, respectively). Laminin β 1 chain has 7 structural domains with different structures, which are different from others β Chain isomers share these structural domains. Laminin, β 1 is expressed in most tissues that produce basement membranes and is one of the three chains that make up laminin 1, which is the first laminin isolated from Engelbreth Holm Swarm (EHS) tumors. β The sequences involved in cell adhesion, chemotaxis, and binding to laminin receptors in the 1 strand have been identified and shown to have the ability to inhibit metastasis.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | CDPGYIGSR |
Sequence(3-letter code) | H-Cys-Asp-Pro-Gly-Tyr-Ile-Gly-Ser-Arg-OH |
Peptide Structure | 
|
Molecular Formula | C40H62N12O14S1 |
Molecular Weight | 967.06 |
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关键字： Laminin (925-933);110590-60-8;层粘连蛋白(925-933);多肽;多肽合成;
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