Host:Rabbit
Target Protein:SGK1
IR:Immunogen Range:301-400/431
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:6446
Swiss Prot:O00141
Source:KLH conjugated synthetic peptide derived from human SGK1:301-400/431
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:SGK1 is a protein kinase that plays an important role in cellular stress response. SGK1 activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. Sustained high levels of SGK1 and activity may contribute to conditions such as hypertension and diabetic nephropathy. This protein also mediates cell survival signals, as it has been shown to phosphorylate and negatively regulate the pro apoptotic FOXO3A protein. Ser 422 is a critical site on the protein and may be involved in its activation.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(2ug/Test)
Cross Reactive Species:Human
Mouse
Rat
Dog
Cow
Horse
本产品仅供科研使用。不能用于人和动物治疗等其它临床诊断使用！
关键字： SGK1;SGK 1;SGK;SGK-1;SGK1_HUMAN;
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