Host:Rabbit
Target Protein:TAK1/MAP3K7
IR:Immunogen Range:
Clonality:Monoclonal
Isotype:IgG
Entrez Gene:6885
Swiss Prot:O43318
Source:KLH conjugated synthetic peptide derived from human TAK1/MAP3K7:
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-1000)
ICC(1:50-100)
IF(1:50-100)
Cross Reactive Species:Human
Mouse
本产品仅供科研使用。不能用于人和动物治疗等其它临床诊断使用!
关键字: Map3k7;MEKK7;TGF1a;Map3k7;TAK1;
上海沪震实业有限公司是一家集研发、生产和销售于一体的生命科学实验室产品生物科技企业。主营产品:试剂盒,ELISA试剂盒,抗体,重组蛋白,血清,胎牛血清,细胞,原代细胞 细胞培养试剂,常用生化试剂。