Host:Rabbit
Target Protein:TNFR1
IR:Immunogen Range:1-100/455
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:7132
Swiss Prot:P19438
Source:KLH conjugated synthetic peptide derived from human TNFR1/TNF Receptor I:1-100/455
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)ELISA(1:5000-10000)Flow-Cyt(1ug/Test)
Cross Reactive Species:HumanMouseRatDogPigCowHorseRabbit
本产品仅供科研使用。不能用于人和动物治疗等其它临床诊断使用!
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