Host:Mouse
Target Protein:PTPN2
IR:Immunogen Range:
Clonality:Monoclonal
Isotype:IgG1/Kappa
Entrez Gene:5771
Swiss Prot:P17706
Source::
Purification:Affinity purified by Protein G
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Multiple alternatively spliced transcript variants encoding different isoforms have been found. Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, respectively, have been reported. [provided by RefSeq, May 2011]
Size:50ul
Concentration:1mg/ml
Applications:WB(1:1000-1:5000)IHC-P(1:50-1:100)ICC(1:50)
Cross Reactive Species:HumanMouseRat
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