Host:Rabbit
Target Protein:Estrogen Receptor alpha + beta
IR:Immunogen Range:201-300/595
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:2099
Swiss Prot:P03372
Source:KLH conjugated synthetic peptide derived from human Estradiol Receptor alpha + beta:201-300/595
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The estrogen receptor (ER) is a 66 kDa protein that mediates the actions of estrogens in estrogen responsive tissues. It is a member of a large superfamily of nuclear hormone receptors that function as ligand activated transcription factors. The ER gene consists of more than 140 kb of genomic DNA divided into 8 exons. These translate into a protein with six functionally discrete domains, labeled A through F. A second form of the estrogen receptor, ER beta has recently been described. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti estrogen (e.g. tamoxifen) therapy.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(1ug/Test)
ICC(1:100)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Pig
![搜狗截图23年05月17日0955_426.png 搜狗截图23年05月17日0955_426.png](/SupplyImg/2023-05-17/6381991416368332699161023.jpg)