Host:Rabbit
Target Protein:Runx3
IR:Immunogen Range:151-250/415
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:864
Swiss Prot:Q13761
Source:KLH conjugated synthetic peptide derived from human Runx3:151-250/415
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Cow
本品仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: Runx3;RUNX3_HUMAN;CBFA3;PEBP2A3;AML2;Oncogene AML-2;PEA2-alpha C; PEBP2-alpha C;
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