Host:Rabbit
Target Protein:PALB2
IR:Immunogen Range:1101-1186/1186
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:79728
Swiss Prot:Q86YC2
Source:KLH conjugated synthetic peptide derived from human PALB2:1101-1186/1186
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the stable intranuclear localization and accumulation of BRCA2. Essential partner of BRCA2 that promotes the localization and stability of BRCA2. Also enables its recombinational repair and checkpoint functions of BRCA2. May act by promoting stable association of BRCA2 with nuclear structures, allowing BRCA2 to escape the effects of proteosome-mediated degradation.
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(1μg/Test)
ICC(1:100)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Pig
Cow
本品仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： DKFZp667I166;4732427B05;BC066140;DKFZp686E1054;FANCN;FLJ21816;OTTMUSP00000025884;PALB2;
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