Product Name:CyclotraxinB
CAS No.:1203586-72-4
Synonyms:TrkB抑制剂多肽
Catalog No.:218P274
Brand:HongTide(上海鸿肽生物)
Description:CyclotraxinB是一种由11个氨基酸组成的环肽(二硫键成环),是一种高效且选择性的TrkB抑制剂,且不会改变 BDNF 的结合。CyclotraxinB能非竞争性地抑制 BDNF 诱导的 TrkB 活性,IC50 值为 0.30 nM。CyclotraxinB也可以穿越血脑屏障,并具有止痛和抗焦虑的行为作用。
CyclotropinB is a cyclic peptide composed of 11 amino acids (disulfide linked to a ring), which is an efficient and selective TrkB inhibitor that does not alter the binding of BDNF. CyclotropinB can non competitively inhibit BDNF induced TrkB activity, with an IC50 value of 0.30 nM. CyclotropinB can also cross the blood-brain barrier and has analgesic and anti anxiety behavioral effects.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | CNPMGYTKEGC(Disulfide bridge:Cys1-Cys11) |
Sequence(3-letter code) | H-Cys-Asn-Pro-Met-Gly-Tyr-Thr-Lys-Glu-Gly-Cys-OH(Disulfide bridge:Cys1-Cys11) |
Peptide Structure | ![CyclotraxinB 1203586-72-4.png CyclotraxinB 1203586-72-4.png](/SupplyImg/2023-06-03/6382142481401027213668299.jpg) |
Molecular Formula | C48H73N13O17S3 |
Molecular Weight | 1200.36 |
订购联系方式:
上海鸿肽生物科技有限公司
手机: +86-18018095145 (同微信号)
QQ: 3259098395
邮箱:sales1@hongtide.com
关键字: 1203586-72-4;CyclotraxinB ;TrkB抑制剂多肽;多肽;多肽合成;
上海鸿肽生物科技有限公司(简称:鸿肽生物)是一家以多肽以及多肽上下游产品研发、生产、销售以及技术转让为主要业 务科技公司。公司现有产品涵盖:定制多肽、目录多肽、氨基酸衍生物、小分子化合物;公司自成立以来,秉持“用质量作船, 以服务为帆,为科研服务”的企业理念,为国内外众多科研工作者提供了优质的服务及产品。