Product Name:Neuropeptide Y Antagonist
CAS No.:158859-98-4
Synonyms:受体拮抗剂多肽GR 231118
Catalog No.:218P312
Brand:HongTide(上海鸿肽生物)
Description:Neuropeptide Y Antagonist是一种有效的神经肽 Y (NPY) Y1 受体拮抗剂多肽(rY1 和 hY1 受体的 pA2 = 10 和 10.5),序列中是一个二聚体多肽,通过酰胺键形成的二聚体多肽。Neuropeptide Y Antagonist也是一种有效和选择性的 NPY Y4 受体激动剂(rY2、hY4 和 rY5 受体的 pEC50 值分别为 6.0、8.6 和 6.1),由同一段序列通过酰胺键形成的二聚体多肽。在体内抑制大鼠的食物摄入,Neuropeptide Y Antagonist在体外也对神经肽 FF (NPFF) 受体具有亲和力 (Ki = 43-73 nM)。
Neuropeptide Y Antagonist is an effective Neuropeptide Y (NPY) Y1 receptor antagonist peptide (pA2 of rY1 and hY1 receptors=10 and 10.5). The sequence is a dimer peptide formed by amide bond. Neuropeptide Y Antigonist is also an effective and selective NPY Y4 receptor agonist (pEC50 values of 6.0, 8.6, and 6.1 for rY2, hY4, and rY5 receptors, respectively), a dimeric peptide formed from the same sequence through amide bonds. Neuropeptide Y Antagonist also has affinity for Neuropeptide FF (NPFF) receptor in vitro (Ki=43-73 nM) by inhibiting food intake of rats in vivo.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | IEP-Dapa-YRLRY-NH2; IEP-Dapa-YRLRY-NH2;Amide Bridge=2-4*, 4-2* |
Sequence(3-letter code) | H-Ile-Glu-Pro-Dapa-Tyr-Arg-Leu-Arg-Tyr-NH2; H-Ile-Glu-Pro-Dapa-Tyr-Arg-Leu-Arg-Tyr-NH2;Amide Bridge=Glu2-Dap4*,Dap4-Glu2* |
Peptide Structure | ![Neuropeptide Y Antagonist 158859-98-4.png Neuropeptide Y Antagonist 158859-98-4.png](/SupplyImg/2023-06-14/6382237275931011705434500.jpg)
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Molecular Formula | C110H170N34O24 |
Molecular Weight | 2352.77 |
订购联系方式:
上海鸿肽生物科技有限公司
手机: +86-18018095145 (同微信号)
QQ: 3259098395
邮箱:sales1@hongtide.com
关键字: 158859-98-4;Neuropeptide Y Antag;受体拮抗剂多肽GR 231118;多肽;多肽合成;
上海鸿肽生物科技有限公司(简称:鸿肽生物)是一家以多肽以及多肽上下游产品研发、生产、销售以及技术转让为主要业 务科技公司。公司现有产品涵盖:定制多肽、目录多肽、氨基酸衍生物、小分子化合物;公司自成立以来,秉持“用质量作船, 以服务为帆,为科研服务”的企业理念,为国内外众多科研工作者提供了优质的服务及产品。