Host:Rabbit
Target Protein:phospho-MARK2 (Ser595)
IR:Immunogen Range:SR(p-S)TF
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:2011
Swiss Prot:Q7KZI7
Source:KLH conjugated Synthesised phosphopeptide derived from human MARK2 around the phosphorylation site of Ser595:SR(p-S)TF
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:MARK2 refers to MAP/microtubule affinity-regulating kinase 2 isoform a [Homo sapiens]. EMK (ELKL Motif Kinase) is a small family of ser/thr protein kinases involved in the control of cell polarity, microtubule. stability and cancer. Several cDNA clones have been isolated that encoded two isoforms of the human ser/thr protein kinase EMK1 called MARK2. These isoforms were characterized by the presence of a 162-bp alternative exon that gave rise to two forms, one containing the exon and the other one lacking it. Both forms were found to be coexpressed in a number of selected cell lines and tissue samples. Human MARK2 was shown to be encoded by a single mRNA ubiquitously expressed. This transcription variant includes the alternative exon in the coding region and therefore codes for a longer protein. Multiple splice variants exist for this protein.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Horse
Sheep
Guinea Pig
本品仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： EMK1;EMK-1;MARK2_HUMAN;Mark2;ELKL motif kinase;phospho-MARK2;ELKL motif kinase 1; MARK2;
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