Product Name:MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2
CAS No.:932391-88-3
Synonyms:FRET底物多肽
Catalog No.:218P324
Brand:HongTide(上海鸿肽生物)
Description:MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2 是严重急性呼吸综合征冠状病毒主蛋白酶 (SARS-CoV Mpro) 的 FRET 底物多肽,序列中含有10个氨基酸。 MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2 底物序列来源于具有 AVLQSGFRK 序列的 SARS-CoV Mpro N 末端自动加工位点的残基 P4-P5'。 MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2 的 Q4 和 S5 之间的酶促裂解释放出高荧光的 7-甲氧基香豆素 (Mca) 基团,该基团受到 2,4-二硝基苯基 (Dnp) 内部猝灭剂的影响,从而产生大量荧光强度增加。
MCA-AVLQSGFR Lys (Dnp) Lys NH2 is a FRET substrate peptide of the main protease of severe acute respiratory syndrome coronavirus (SARS-CoV Mpro), with a sequence containing 10 amino acids. The substrate sequence of MCA-AVLQSGFR-Lys (Dnp) - Lys-NH2 is derived from the residue P4-P5 'of SARS-CoV Mpro N-terminal automatic processing site with AVLQSGFRK sequence. The enzymatic cleavage between Q4 and S5 of MCA-AVLQSGFR-Lys (Dnp) - Lys-NH2 explains that it emits a highly fluorescent 7-neneneba methoxy Coumarin (Mca) group, which is affected by the internal quenching agent of 2,4-dinitrophenyl (Dnp), resulting in a large increase in fluorescence intensity.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | Mca-AVLQSGFR-Lys(Dnp)-K-NH2 |
Sequence(3-letter code) | Mca-Ala-Val-Leu-Gln-Ser-Gly-Phe-Arg-Lys(Dnp)-Lys-NH2 |
Peptide Structure |
|
Molecular Formula | C69H99N19O15 |
Molecular Weight | 1514.7 |
订购联系方式:
上海鸿肽生物科技有限公司
手机: +86-18018095145 (同微信号)
QQ: 3259098395
邮箱:sales1@hongtide.com
关键字: 932391-88-3;FRET底物多肽;MCA-AVLQSGFR-Lys(Dnp;多肽;多肽合成;
上海鸿肽生物科技有限公司(简称:鸿肽生物)是一家以多肽以及多肽上下游产品研发、生产、销售以及技术转让为主要业 务科技公司。公司现有产品涵盖:定制多肽、目录多肽、氨基酸衍生物、小分子化合物;公司自成立以来,秉持“用质量作船, 以服务为帆,为科研服务”的企业理念,为国内外众多科研工作者提供了优质的服务及产品。