Host:Rabbit
Target Protein:APEX2
IR:Immunogen Range:301-400/518
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:27301
Swiss Prot:Q9UBZ4
Source:KLH conjugated synthetic peptide derived from human APEX2:301-400/518
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes a protein shown to have a weak class II AP endonuclease activity. Most of the encoded protein is located in the nucleus but some is also present in mitochondria. This protein may play an important role in both nuclear and mitochondrial base excision repair (BER).
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
Cross Reactive Species:Human
Mouse
Rat
![搜狗截图23年06月20日1649_59.png 搜狗截图23年06月20日1649_59.png](/SupplyImg/2023-06-20/6382287659541881449405908.jpg)
本品仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: APEX2;APE2;APE 2;APEXL2;APEX L2;APEXL 2;C430040P13Rik;XTH2;
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