114870-03-0 磺达肝癸钠

生物活性 Fondaparinux sodium is an antithrombin-dependent factor Xa inhibitor. IC50 & Target Factor Xa[1] 体外研究 (In Vitro) Fondaparinux sodium is the first agent of a new class of anticoagulants that selectively target factor Xa. For Fondaparinux, its IC50 values (anti-Xa IU/ml) are 0.59±0.05 for activated monocytes (ac-M) and 0.17±0.03 for monocyte-derived microparticles (MMPs)[2]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. 体内研究 (In Vivo) Fondaparinux sodium has a linear, dose-dependent pharmacokinetic profile, which provides a highly predictable response. Fondaparinux sodium is 100% bioavailable, has a rapid onset of action, and has a half-life of 14 to 16 hours, allowing for sustained antithrombotic activity over a 24-hour period. The drug does not affect prothrombin time or activated partial thromboplastin time, nor does it affect platelet function or aggregation. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

上海芮晖化工科技有限公司是一家立足中国、面向世界的药物化学高新技术企业；公司位于上海市浦东外高桥保税区，主要致力于高端活性小分子类产品及关键中间体的开发和销售，公司秉承务实，诚信原则，承接小分子抑制剂、API、杂质对照品及关键中间体的外包定制和产品小试，中试，大生产工艺开发及转让服务。 芮晖主要由留学博士、硕士等一批有着丰富有机合成经验的高端人才组成，大多数人有着在知名CRO公司从业的背景。目前，公司已与欧美制药公司、科研机构、进出口商建立了稳定的业务往来。 芮晖视产品质量为公司的生命，产品的纯度、稳定性是我们所关注的焦点，为了确保能向顾客提供优质的产品，我们对产品进行严格的质量控制，在交付前为