Rabbit Anti-Phospho-EIF2S1 (Ser51) Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:Phospho-EIF2S1 (Ser51)
IR:Immunogen Range:EL(p-S)RR
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:1965
Swiss Prot:P05198
Source:KLH conjugated synthesised phosphopeptide derived from human eIF2 alpha around the phosphorylation site of Ser51:EL(p-S)RR
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM, Feb 2010]
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Cow
本品仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: Phospho-EIF2S1 (Ser5;EIF2S1 (phospho S51);EIF2S1 ;EIF2A;CDA 02;CDA02;eIF 2 alpha;EIF 2;
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