Rabbit Anti-ASCL2 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:ASCL2
IR:Immunogen Range:51-120/193
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:430
Swiss Prot:Q99929
Source:KLH conjugated synthetic peptide derived from Human ASCL2:51-120/193
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Members of the myogenic determination family are basic helix-loop-helix (bHLH) proteins that can be separated into two classes, both of which work together to activate DNA transcription. Class A proteins include the ubiquitously expressed E-box binding factors, namely E2A, ITF-2 and HEB, while class B proteins, such as MyoD, myogenin and Neuro D (BETA2), are transiently expressed and exhibit a much more limited tissue distribution. Working in opposition to these positively acting factors are a specialized group of basic helix-loop-helix (bHLH) transcription factors that function as dominant negative regulators and are involved in cell lineage determination and differentiation. ASCL2 is a 193 amino acid protein that localizes to the nucleus and contains one bHLH domain. Expressed in developing placental tissue, ASCL2 binds to DNA and functions as a transcriptional regulator that is involved in the maturation of neuronal precursors in the peripheral and central nervous systems
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(2ug/Test)
ICC(1:100)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Pig
Cow
本品仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: ASCL2;Achaete scute comple;Achaete scute homolo;chaete-scute complex;Achaete-scute homolo;ASCL2;ASCL2_HUMAN; ASH-2;
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