Rabbit Anti-EphB2 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:EphB2
IR:Immunogen Range:101-200/1055
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:2048
Swiss Prot:P29323
Source:KLH conjugated synthetic peptide derived from human EphB2:101-200/1055
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a transmembrane region and an intracellular kinase domain. They bind ligands called ephrins and are involved in diverse cellular processes including motility, division, and differentiation. A distinguishing characteristic of Eph-ephrin signaling is that both receptors and ligands are competent to transduce a signaling cascade, resulting in bidirectional signaling. This protein belongs to a subgroup of the Eph receptors called EphB. Proteins of this subgroup are distinguished from other members of the family by sequence homology and preferential binding affinity for membrane-bound ephrin-B ligands. Allelic variants are associated with prostate and brain cancer susceptibility. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015]
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
本品仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： EphB2;PHB2_HUMAN;Ephrin type-B recept;EC:2.7.10.1;EphB2/CTF1; EphB2/CTF2;DRT;EPHT3;
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