Rabbit Anti-TRAF1 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:TRAF1
IR:Immunogen Range:301-416/416
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:7185
Swiss Prot:Q13077
Source:KLH conjugated synthetic peptide derived from human TRAF1:301-416/416
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins; this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors. [provided by RefSeq].
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Cow
Horse
Rabbit
本品仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： TRAF1;TNF receptor-associa;4732496E14Rik;EBV induced protein ;Epstein-Barr virus-i;Tnf receptor associa;TRAF 1;TRAF1_HUMAN;
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