Rabbit Anti-CDC42 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:CDC42
IR:Immunogen Range:101-191/191
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:998
Swiss Prot:P60953
Source:KLH conjugated synthetic peptide derived from human CDC42:101-191/191
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20. [provided by RefSeq, Apr 2013].
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Pig
Cow
Horse
Rabbit
本品仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： CDC42;CDC 42;CDC42Hs;Cell division cycle ;Cell division cycle ;dJ224A6.1.1;dJ224A6.1.2;CDC42_HUMAN;
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