Rabbit Anti-ST2 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:ST2
IR:Immunogen Range:1-100/556
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:9173
Swiss Prot:Q01638
Source:KLH conjugated synthetic peptide derived from human ST2 (isoform A,B,C):1-100/556
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:ST2 is a member of a superfamily containing the Interleukin 1 (IL1) receptor and the Toll-like receptors (TLRs). The TLRs are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. ST2 was originally identified as a protein whose production was stimulated by various proliferation-inducing agents such as PDGF and FGF. More recently, it has been shown to negatively regulate IL1 receptor and Toll-like receptor 4 (TLR4) signaling and to maintain endotoxin tolerance. It has been suggested that the inhibition of TLR4 signaling occurs through the association and sequestering of TLR adaptor molecules such as MyD88 and TIRAP.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
本品仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： ST2;DER-4;FIT 1;Protein ST2;ST2;ST2L;ST2V;Ste2;
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