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DATASHEET
Rabbit Anti-HLA-DRA Polyclonal Antibody
Host:Rabbit
Target Protein:HLA-DRA
IR:Immunogen Range:1-100/254
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:3122
Swiss Prot:P01903
Source:KLH conjugated synthetic peptide derived from human HLA-DRA:1-100/254
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5. [provided by RefSeq]
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
Flow-Cyt(1μg/Test)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Horse
Sheep
本品仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: HLA-DRA;DR alpha chain;DRB1;DRB4;HLA class II histoco; HLA class II histoc;HLA DR1B;HLA DRA1;
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