Rabbit Anti-CXCR3 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:CXCR3
IR:Immunogen Range:301-367/367
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:12766
Swiss Prot:O88410
Source:KLH conjugated synthetic peptide derived from mouse CXCR3:301-367/367
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716). [provided by RefSeq, Jun 2011].
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Rabbit
Guinea Pig
本品仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: CXCR3;C-X-C chemokine rece;IP-10 receptor;CD 183;CD183;CD183 antigen;CKRL2;CXCR3_HUMAN;
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