Rabbit Anti-GDF15 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:GDF15
IR:Immunogen Range:221-308/308
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:9518
Swiss Prot:Q99988
Source:KLH conjugated synthetic peptide derived from human GDF-15:221-308/308
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Growth differentiation factor 15 (GDF15) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. It has been implicated in a variety of functions directly related to tumorigenicity including antiproliferative and pro-apoptotic effects. BMP proteins are secreted growth factors that are characterized by seven conserved cysteine residues. In general, they are regulators of cell growth and differentiation in both embryonic and adult tissues. GDF15 is an important downstream mediator of DNA damage signaling and a transcriptional target of p53.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
本品仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: GDF15;GDF 15;GDF-15;Growth differentiati;NRG1;NSAID;NSAID regulated prot;GDF15_HUMAN;
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