Rabbit Anti-TXNIP Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:TXNIP
IR:Immunogen Range:101-200/391
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:10628
Swiss Prot:Q9H3M7
Source:KLH conjugated synthetic peptide derived from human TXNIP:101-200/391
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:TXNIP may act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. It interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. It functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. It is required for the maturation of natural killer cells (from SwissProt).
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Rabbit
本品仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： TXNIP;THIF;thioredoxin binding ;Thioredoxin-binding ;upregulated by 1,25-;VDUP1;Vitamin D3 ;TXNIP_HUMAN;
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