Rabbit Anti-CARD15/NOD2 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:CARD15/NOD2
IR:Immunogen Range:251-350/1040
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:64127
Swiss Prot:Q9HC29
Source:KLH conjugated synthetic peptide derived from human CARD15:251-350/1040
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Defects in NOD2 are the cause of sarcoidosis early-onset (EOS) . EOS is a form of sarcoidosis manifesting in children younger than 4 years of age. Sarcoidosis is an idiopathic, systemic, inflammatory disease characterized by the formation of immune granulomas in involved organs. Granulomas predominantly invade the lungs and the lymphatic system, but also skin, liver, spleen, eyes and other organs may be involved. Early-onset sarcoidosis is quite rare and has a distinct triad of skin, joint and eye disorders, without apparent pulmonary involvement. Compared with an asymptomatic and sometimes naturally disappearing course of the disease in older children, early-onset sarcoidosis is progressive and in many cases causes severe complications, such as blindness, joint destruction and visceral involvement.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Horse
Rabbit
本品仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: CARD15/NOD2;ACUG;BLAU;CARD15;Caspase recruitment ;Nod2;NOD2 protein;NOD2_HUMAN;
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