Rabbit Anti-VWF Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:VWF
IR:Immunogen Range:351-450/2813
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:7450
Swiss Prot:P04275
Source:KLH conjugated synthetic peptide derived from human Von Willebrand Factor:351-450/2813
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Von Willebrand Factor (VWF) was previously known as Factor VIII related antigen. VWF is synthesized exclusively by endothelial cells and megakaryocytes, and stored in the intracellular granules or constitutively secreted into plasma. This glycoprotein functions as both an antihemophilic factor carrier and a platelet vessel wall mediator in the blood coagulation system. Important in the maintenance of homeostasis, it participates in platelet vessel wall interactions by forming a noncovalent complex with coagulation factor VIII at the site of vascular injury. The Von Willebrand factor has functional binding domains to platelet glycoprotein Ib, glycoprotein IIb/IIIa, collagen and heparin. Mutations in this gene or deficiencies in this protein result in Von Willebrand's disease. VWD is characterized by frequent bleeding (gingival, minor skin quantitative lacerations, menorrhagia, etc.).
Size:50ul
Concentration:1mg/ml
Applications:IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(3ug/Test)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Rabbit
本品仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： VWF;Coagulation factor V;F8VWF;Factor VIII related ;von Willebrand antig; Von Willebrand anti;VWD;VWF_HUMAN;
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