Rabbit Anti-Ghrelin Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:Ghrelin
IR:Immunogen Range:31-117/117
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:51738
Swiss Prot:Q9UBU3
Source:KLH conjugated synthetic peptide derived from human Ghrelin:31-117/117
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes ghrelin-obestatin preproprotein, which generates ghrelin and obestatin. Ghrelin is an endogenous ligand for the growth hormone secretagogue receptor and is involved in regulating growth hormone release. Obestatin was initially reported to be an endogenous ligand for the orphan G protein-coupled receptor GPR39 and was involved in satiety and decreased food intake; however, these findings are controversial. Recent reports show that obestatin is involved in inhibiting thirst and anxiety, improving memory, regulating sleep, affecting cell proliferation, and increasing the secretion of pancreatic juice enzymes. Alternative promoters and alternative splicing result in multiple transcript variants, some of which encode different protein isoforms and some of which do not encode a protein but may regulate the ghrelin-obestatin preproprotein expression. In addition, antisense transcripts for this gene have been identified and may also function in regulation of the ghrelin-obestatin preproprotein expression. [provided by RefSeq, Oct 2008].
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Horse
Rabbit
Sheep
本品仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: Ghrelin;Ghrelin 27;Appetite regulating ;Ghrelin 28;Ghrelin/obestatin pr;GHRL;UNQ524;GHRL_HUMAN;
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