Product Name:Dabcyl-Gaba-SQNYPIVQ-Edans
CAS No.:127134-13-8
Synonyms:淬灭受体组合肽
Catalog No.:162P11
Brand:HongTide(上海鸿肽生物)
Description:Dabcyl-Gaba-SQNYPIVQ-Edans是荧光HIV-1蛋白酶底物多肽,由一个八肽与一个荧光供体(EDANS)和一个淬灭受体(DABCYL)组成,连接在 COOH-和 NH2-末端。Dabcyl-Gaba-SQNYPIVQ-Edans的序列中插入 γ-Abu 间隔物以避免大受体对底物结合的潜在空间位阻,这种 FRET 底物在 Tyr-Pro 键上被 HIV-1 蛋白酶切割,导致荧光强度随时间增加;Dabcyl-Gaba-SQNYPIVQ-Edans的激发波长为 340 nm,发射波长为 490 nm。
Dabcyl-Gaba-SQNYPIVQ-Edans is a fluorescent HIV-1 protease substrate peptide, which is composed of an octapeptide, a fluorescent donor (EDANS) and a quenched receptor (DABCYL), connected to the COOH - and NH2- terminals. Insertion into the sequence of Dabcyl Gaba SQNYPIVQ Edans γ- Abu spacer to avoid the Potential space steric hindrance of large receptors to substrate binding. This FRET substrate is cut by HIV-1 protease on the Tyr-Pro bond, resulting in an increase in fluorescence intensity over time; The excitation wavelength of Dabcyl-Gaba-SQNYPIVQ-Edans is 340 nm, and the emission wavelength is 490 nm.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | Dabcyl-Gaba-SQNYPIVQ-Edans |
Sequence(3-letter code) | Dabcyl-γ-Abu-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Edans |
Peptide Structure | ![Dabcyl-Gaba-SQNYPIVQ-Edans 127134-13-8.png Dabcyl-Gaba-SQNYPIVQ-Edans 127134-13-8.png](/SupplyImg/2023-07-17/6382520645949541502557936.jpg)
|
Molecular Formula | C73H97N17O18S |
Molecular Weight | 1532.74 |
订购联系方式:
上海鸿肽生物科技有限公司
手机: +86-18018095145 (同微信号)
QQ: 3259098395
邮箱:sales1@hongtide.com
关键字: Dabcyl-Gaba-SQNYPIVQ;127134-13-8;淬灭受体组合肽;多肽;多肽合成;
上海鸿肽生物科技有限公司(简称:鸿肽生物)是一家以多肽以及多肽上下游产品研发、生产、销售以及技术转让为主要业 务科技公司。公司现有产品涵盖:定制多肽、目录多肽、氨基酸衍生物、小分子化合物;公司自成立以来,秉持“用质量作船, 以服务为帆,为科研服务”的企业理念,为国内外众多科研工作者提供了优质的服务及产品。