Rabbit Anti-SYK Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:SYK
IR:Immunogen Range:501-600/635
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:6850
Swiss Prot:P43405
Source:KLH conjugated synthetic peptide derived from human SYK:501-600/635
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Syk (72 kDa) is a non receptor protein tyrosine kinase that plays an important role in immune receptor signal transduction and is implicated in endothelial cell functions, including cell growth and migration. SYK is a positive effector of BCR stimulated responses. It couples the B cell antigen receptor (BCR) to the mobilization of calcium ions either through a phosphoinositide 3 kinase dependent pathway, when not phosphorylated on tyrosines of the linker region, or through a phospholipase C gamma dependent pathway, when phosphorylated on Tyr 342 and Tyr 346. Thus the differential phosphorylation of SYK can determine the pathway by which BCR is coupled to the regulation of intracellular calcium ions. Alternate Names: p72syk; Spleen tyrosine kinase; Tyrosine protein kinase SYK
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
本品仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： SYK;Tyrosine-protein kin;Spleen tyrosine kina;Contains;72kDa tyrosine-prote;40 kDa tyrosine-prot;SYK;KSYK_HUMAN;
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