Rabbit Anti-TIE2 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:TIE2
IR:Immunogen Range:401-550/1120
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:7010
Swiss Prot:Q02763
Source:KLH conjugated synthetic peptide derived from human Tie2:401-550/1120
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis.TEK is closely related to the TIE receptor tyrosine kinase.
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(3ug/Test)
ICC(1:100)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Pig
Cow
Horse
本品仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: TIE2;Angiopoietin-1 recep; Tyrosine-protein ki;hTIE2;CD202b;VMCM1;VMCM;TIE2_HUMAN;
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