Rabbit Anti-HPV16 E6 + HPV18 E6 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:HPV16 E6 + HPV18 E6
IR:Immunogen Range:
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:1489078
Swiss Prot:P03126
Source:KLH conjugated synthetic peptide derived from human HPV16 E6+ HPV18 E6:
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Human Papilloma virus (HPV) is responsible for the development of type and tissue specific papilloma in the oral cavity and in the larynx. In the skin papilloma virus can cause different types of warts and in the ano-genital region it is associated with condyloma or carcinoma. HPV types 1,6 and 11 usually are associated with benign transformations of the tissues, while e.g. HPV types 16, 18 and 31 seem to be responsible for the development of some carcinoma like cervical carcinoma. The role of HPV in non-melanoic tumours of the skin is under discussion.
Protein E6 is a Transcriptional transactivator, binding double stranded DNA. It has transforming activity inactivating, with E6-AP ubiquitin-protein ligase, the human TP53/p53 tumor suppressor protein by targeting it for degradation.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(1ug/Test)
IF(1:100-500)
Cross Reactive Species:Human
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本品仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： HPV16 E6 + HPV18 E6;HPV16 E6;HPV16+HPV18 E6;HPV16/18 protein;Human Papilloma viru;E6;papillomavirus type ;Protein E6;
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