Rabbit Anti-DGAT1 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:DGAT1
IR:Immunogen Range:251-350/488
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:8694
Swiss Prot:O75907
Source:KLH conjugated synthetic peptide derived from human DGAT1:251-350/488
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Glucose and insulin are anabolic signals which upregulate the transcriptions of a series of lipogenic enzymes to convert excess carbohydrate into triglycerides for efficient energy storage. DGAT1 is a microsomal enzyme that assists in the synthesis of fatty acids into triglycerides. DGAT catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol (DAG) and fatty acyl CoA as substrates. DGAT plays a fundamental role in the metabolism of cellular diacylglycerol and is important in higher eukaryotes for physiologic processes involving triacylglycerol metabolism such as intestinal fat absorption, lipoprotein assembly, adipose tissue formation, and lactation. DGAT1 is involved in fat absorption in the intestine and in basal level triglyceride synthesis in adipose tissue, where it is more highly expressed.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Horse
本品仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: DGAT1;ACAT related gene pr; ACAT-related gene p;ARAT;ARGP1;C75990;D15Ertd23e;hCG_24006;
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